What is Advanced Prostate Cancer?

Advanced prostate cancer is when the cancer has spread outside of the prostate (metastatic disease) or shows signs of spreading after using hormonal therapy (castrate resistant prostate cancer CRPC).

What is Castrate-Resistant Prostate Cancer (CRPC)?

Castrate-resistant prostate cancer (CRPC) is when your PSA has risen or your cancer has shown signs of growing after hormone therapy. Prostate cancer usually responds to hormone therapy, but eventually cancer cells will “outsmart” the treatment. They can learn to grow even without testosterone to fuel their growth.

What is Metastatic Castrate-Resistant Prostate Cancer (mCRPC)?

Metastatic castrate-resistant prostate cancer or mCRPC is when your PSA has risen while on hormone therapy and your cancer has spread far from the prostate. Many of the newest treatments available are for patients with mCRPC.

What is Biochemical Recurrence?

Biochemical recurrence is when your PSA has risen after initial treatment and you have no other sign of cancer. The hormone therapy section of this booklet will help you understand treatments available to you.